Updating the concept of prebiotics
Here is a brief history of what has happened and where to look for my latest thoughts: The birth of the blog Seven years ago, I thought that I could continue to update this treatise as I followed the key scientific streams related to health and aging.Soon, I discovered that for older people, creating health and creating longevity amount to the same thing.For example, REDOX processes, central to the first theory of aging, actually play significant roles in each of the other theories.
These include progress in stem cell research, many topics of epigenetics, several key gene-activation pathways, mitochondrial dynamics, redox related pathways, telomere-related pathways, health-producing properties of plant polyphenols, stress-responses and hormesis, quorum sensing in biofilms, microtubules, bacterial communications, nano delivery of therapeutic substances, quantum biology, systems biology, human bacterial biomes, roles of RNA species, age-related diseases including Alzheimers, Parkinsons, diabetes and cancers, evolutionary origins of our signaling systems, exosomal communication systems, cell senescence, signaling gasses, interspecies communications, circadian regulation and progress towards creating a Grand Unified Theory of biology and aging - to mention just a few.
As time has progressed my appreciation and understanding of the detailed sciences involved in aging and health have multiplied severalfold.
And yet, the more I learn the more obvious it is that there is much more yet to be learned.
A comprehensive document for the benefit of people interested in living very long healthy lives and who are willing to adapt emerging knowledge personally to do so.  FORWARD VIEW FROM JULY 2014 More than six years have elapsed from drafting the initial version of this treatise and despite many updates parts of it show age.
Many topics and insights I would now include are missing.And, to know how to do that based on new scientific discoveries, it was necessary to consider vast, disparate and detailed bodies of scientific knowledge.